Flora Ogbenyeanu Ogoegbunam Azikiwe (August 7, 1917 – August 22, 1983) was the first wife of Nnamdi Azikiwe, the first president of Nigeria.
She was First Lady of Nigeria from October 1, 1963, to January 16, 1966. Ogoegbunam was born in Onitsha, a town in present-day Anambra State, to Chief Ogoegbunam, an Adazii of Onitsha (Chief Ndichie) of Ogboli Agbor Onitsha. There she met Nnamdi Azikiwe in 1934 and they married on April 4, 1936.
Their wedding took place at Wesley Church James Town in Accra on the Gold Coast (now Ghana), where her husband was then working as editor of the African Morning Post. Ogoegbunam was a member of the Eastern Working Committee of the National Council of Nigeria and Cameroon (NCNC), she was the first patron of the Society of Home Sciences
(HSA), formerly known as Federal Home Science Club
She died on August 22, 1983 at the age of 66. She and her husband had a daughter and three sons.